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Northern Health Library: Step on Sepsis


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Websites and organisations

Australian Commission on Safety and Quality in Health Care - Sepsis Clinical Care Standard

The Sepsis Clinical Care Standard ensures that a patient presenting with signs and symptoms of sepsis receives optimal care, from symptom onset through to discharge from hospital and survivorship care.

  • Sepsis Clinical Care Standard 2022
    The Sepsis Clinical Care Standard will help to ensure sepsis is recognised early and patients receive coordinated, best-practice care so that the risk of death or ongoing morbidity is reduced. This includes timely recognition of sepsis, early and appropriate antimicrobial therapy and continuity of care from the acute setting through to discharge and survivorship.
     

Australian Sepsis Network

Sepsis Australia works with collaborating partners in the Australian Sepsis Network (ASN) to leverage, emulate and propagate best practices for sepsis. 
 

Australian Sepsis Grand Round

The Australian Sepsis Grand Round (ASGR) is a free online event series dedicated to advancing best-practice sepsis care and fostering collaboration among healthcare professionals. Since its inception as the Victorian Sepsis Grand Round in 2021, ASGR has become a hub for knowledge exchange and professional development, uniting clinicians from Australia and worldwide.
 

Global Sepsis Alliance (GSA)

The GSA is made up of 7 regional sepsis alliances to work closer with local stakeholders, regional governments, and regional WHO offices, and to enact key performance indicators from the WHA Sepsis Resolution adopted by the WHO in May 2017.
 

Royal Children's Hospital - Paediatric sepsis

Guidelines for the assessment and management of children with sepsis, created by the Royal Children's Hospital.
 

Society of Critical Medicine- Surviving Sepsis Campaign (SSC)

The international Surviving Sepsis Campaign (SSC) is a joint initiative of the Society of Critical Care Medicine (SCCM) and the European Society of Intensive Care Medicine (ESICM), led by multidisciplinary international experts who are committed to reducing mortality and morbidity from sepsis and septic shock, which are leading causes of death worldwide.

PROMPT Guidelines

These guidelines are available in PROMPT or click on the links below to access.

Sepsis Management - Adult

Infection - Antimicrobial Prescribing Guide

Deteriorating Patient / Escalation of Clinical Care

NH resources (intranet)

You will need to be using a Northern Health network computer or FollowMe Desktop to access these links.

Information about Standards:

September is World Sepsis Awareness month! 
Stay tuned for exciting events happening across NH campuses. Don’t miss out on opportunities to learn, engage, and raise awareness about sepsis!
 

Current literature

Dark, P., Hossain, A., McAuley, D. F., Brealey, D., Carlson, G., Clayton, J. C., Felton, T. W., Ghuman, B. K., Gordon, A. C., Hellyer, T. P., Lone, N. I., Manazar, U., Richards, G., McCullagh, I. J., McMullan, R., McNamee, J. J., McNeil, H. C., Mouncey, P. R., Naisbitt, M. J., Parker, R. J., … ADAPT-Sepsis Collaborators (2025). Biomarker-Guided Antibiotic Duration for Hospitalized Patients With Suspected Sepsis: The ADAPT-Sepsis Randomized Clinical Trial. JAMA333(8), 682–693. https://doi.org/10.1001/jama.2024.26458

Li, Q., Zhou, Q., Fan, J., Huang, S., Chen, Y., Song, F., Fu, Z., Liu, E., Tang, D., Zeng, L., & Luo, Z. (2025). Oral switch vs. continued intravenous antibiotic therapy in patients with bacteraemia and sepsis: a systematic review and meta-analysisClinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases31(4), 551–559. https://doi.org/10.1016/j.cmi.2024.11.035

Long, B., & Gottlieb, M. (2025). Emergency medicine updates: Management of sepsis and septic shockThe American journal of emergency medicine90, 179–191. https://doi.org/10.1016/j.ajem.2025.01.054

Tang, F., Yuan, H., Li, X., & Qiao, L. (2024). Effect of delayed antibiotic use on mortality outcomes in patients with sepsis or septic shock: A systematic review and meta-analysisInternational immunopharmacology129, 111616. https://doi.org/10.1016/j.intimp.2024.111616